Fries, Timothy C. (2023) The Association Between The Inflammation Model of Depression, Race, and Gender. Honours thesis, University of Southern Queensland. (Unpublished)
Abstract
Depression, a pervasive condition affecting millions globally, imposes a significant economic and social burden. Early identification and effective interventions are urgently needed for the three out of ten depressed clients experiencing inflammation �associated treatment resistance. Utilizing the Inflammation Model of Depression framework, this study aims to clarify the relationship between inflammation, with both severity and type of depressive symptoms, in a large, racially diverse, cross-section of
US residents (N = 4,865). The current study tests five hypotheses, primarily focusing on the association between inflammation, severity and type of depressive symptoms, with
stratification by gender and race. Menopausal stage was explored as a potential moderator of the relationship between testosterone and depressive symptoms. The
study found a small but significant positive correlation between CRP levels with both somatic and overall depressive symptoms. Women with high levels of CRPs were more
likely to report moderate to severe depressive symptoms. This association varied by racial strata. Menopausal stage served as a weak but significant moderator of the
relationship between testosterone levels and depressive symptoms in women. The current study is the first to investigate the relationship between inflammation and
depression in the Asian American population, finding this sub-population differed significantly from the study’s average. The findings underscore the utility of examining
depression through the Inflammation Model of Depression framework within a biopsychosocial approach. Findings from the current study could support earlier identification of clients at risk of developing treatment resistant depression and inform clinical practice.
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| Item Type: | Thesis (Non-Research) (Honours) |
|---|---|
| Item Status: | Live Archive |
| Additional Information: | Current UniSQ staff and students can request access to this thesis. Please email research.repository@unisq.edu.au with a subject line of SEAR thesis request and provide: Name of the thesis requested and Your name and UniSQ email address |
| Faculty/School / Institute/Centre: | Current – Faculty of Health, Engineering and Sciences - School of Psychology and Wellbeing (1 Jan 2022 -) |
| Supervisors: | Daniel Joyce |
| Date Deposited: | 19 May 2025 23:12 |
| Last Modified: | 19 May 2025 23:12 |
| Uncontrolled Keywords: | Depression, Inflammation, Asian Americans, Somatic Symptoms |
| Fields of Research (2008): | 17 Psychology and Cognitive Sciences > 1799 Other Psychology and Cognitive Sciences > 179999 Psychology and Cognitive Sciences not elsewhere classified |
| Fields of Research (2020): | 52 PSYCHOLOGY > 5299 Other psychology > 529999 Other psychology not elsewhere classified |
| URI: | https://sear.unisq.edu.au/id/eprint/52332 |
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