Investigation into the non-invasive monitoring of blood glucose levels in people with diabetes

Gillies, Ross Donald (2005) Investigation into the non-invasive monitoring of blood glucose levels in people with diabetes. [USQ Project]


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Diabetes Mellitus is a condition that reduces the body's ability to maintain normal blood
glucose levels. Maintaining the correct blood glucose level is important as it provides different
parts of the body with energy to function properly. Because of this, diabetics must be able to
know what the levels are, so they can control them with supplements or other treatments.
At present, people with diabetes must monitor their blood glucose levels using invasive
techniques like needles and pin-prick devices sometimes up to three or four times a day,
depending on the severity of their condition. Because of the pain and inconvenience of testing
using this method, sufferers don't always test themselves as often as they should.
A non-invasive, in vivo system of monitoring blood glucose levels is the vision of this
investigation. Being non-invasive would make the task of measuring blood sugar painless. In
vivo, in a clinical testing sense means constantly monitoring. This is in contrast to the in vitro
method commonly used today where blood is extracted with the needle or pin-prick and
analysed. As much a problem as pain for the diabetic is the inconvenience of having to stop
what they are doing and test themselves. A solution could be a device which constantly
monitors without being prompted by the user. An in vivo system has advantages as it could be
used in the future to provide a closed-loop insulin delivery system (i.e an artificial pancreas),
and it can provide alarms for hypoglycaemic (low glucose) and hyperglycaemic (too much
glucose) attacks.
There have been some studies into using near-infrared light to measure the glucose levels, but
as yet this method is not accurate enough for clinical applications. This project will investigate
the method and determine if there are any ways to improve the quality of signals or similar

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Item Type: USQ Project
Refereed: No
Item Status: Live Archive
Faculty/School / Institute/Centre: Historic - Faculty of Engineering and Surveying - Department of Mechanical and Mechatronic Engineering (Up to 30 Jun 2013)
Date Deposited: 11 Oct 2007 00:26
Last Modified: 02 Jul 2013 22:33
Uncontrolled Keywords: Diabetes Mellitus, glucose levels, in vivo system of monitoring blood glucose levels, non-invasive monitoring of blood glucose levels, pin-prick devices, blood glucose monitoring
Fields of Research (2008): 09 Engineering > 0903 Biomedical Engineering > 090304 Medical Devices
Fields of Research (2020): 40 ENGINEERING > 4003 Biomedical engineering > 400308 Medical devices

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